Systemic Inflammatory Response Syndrome and Postoperative Complications After Orthognathic Surgery

tatements of the problem：Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting imme- diately after surgery have lately been regarded as potential warnings of impending post- operative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Method of data analysis：244 patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2011 were involved in this study. Results of investigation：A the search  based on the SIRS diagnostic criteria resulted in assignment of 50 cases to the SIRS group and 194 cases to the non-SIRS group. Postoperative complications occurred in 34.0% of the SIRS group and 10.3% of the non-SIRS group . In four cases, a postoperative fluctuation in IL-6 level evaluated. Conclusions relevant to the problem：These results suggest the importance of careful management of postoperative SIRS patients in preventing complications. References：1) Bone RC (1992) Toward an epidemiology and natural history of SIRS. JAMA 268:3452–3455. 2) Yajima Y, Noma H, Kasahara K, Takeda E (2000) Systemic inframmatory response syndrome and postoperative complications after oral cancer surgery. Bull Tokyo Dent Coll 41:187– 194.