Female Patients with Oral Squamous Cell Carcinoma in Japan
The aim of this study is to determine the incidence of oral squamous cell carcinoma in Japanese female patients.
Materials and methods
The subjects were 760 patients who treated during January 1987 through December 2012 in our institution. Annual transition was considered, it asked for the approximation straight line. The relevancy of calculated female and prognosis (Overall survival : OS, disease free survival : DFS) were evaluated.
Result
A total of 760 patients treated for oral squamous cell carcinoma in 26 years were included. Mean age was 62.7 (range 18-94). Median follow-up period was 35.8 months. 5-year OS was 83.8% and 5-year DFS was 77.4%.
41.2% of patients were female. Male to female ratio was 1.43. Ratio of female increased significantly (r = 0.419, p = 0.033**, y = 0.0064x + 0.3003). Mean age was 65.2 (range 26-94). Stage I, II, III and IV were 26.2%, 48.2%, 11.8% and 11.5%, respectively.
5-year OS was 81.4% in female and 86.4% in male, respectively (p = 0.1529). 5-year DFS was 76.5% in female and 73.9% in male, respectively (p = 0.2000). It was determined that better DFS observed in female patients with oral squamous cell carcinoma. However it was no significant.
Conclusion
In Japan, the ratio of female increased significantly in recent years. 5-year OS and DFS of female patients were 81.4%, 76.5%, respectively.