A Clinical Analysis of Minor Dental Surgery in Patients Taking New Oral Anticoagulant Drugs

Yago, Kaori

A Clinical Analysis of Minor Dental Surgery in Patients Taking New Oral Anticoagulant Drugs

Kaori Yago , Department of Oral Surgery, Mita Hospital, International Health and Welfare, Tokyo, Japan

Soichiro Asanami , Department of Oral Surgery, Mita Hospital, International Health and Welfare, Tokyo, Japan

Yoshiaki Kawamoto , ）Department of Oral Surgery, Mita Hospital, International Health and Welfare, Tokyo, Japan

Hayato Hashiguchi , Department of Oral Surgery, Mita Hospital, International Health and Welfare, Tokyo, Japan

Hideki Kizu , Department of Oral Surgery, Tachikawa Kyosai Hospital, Tokyo, Japan

Masatsugu Otaishi , Department of Oral Surgery, Hino Municipal Hospital, Tokyo, Japan

<Objectives>

Along with the arrival of a super-aging society, patients taking antithrombotic drugs such as warfarin, aspirin, etc. are increasing. In Japan, warfarin was the only oral anticoagulant drug for a long time, but a new oral anticoagulant drug has been available for use since 2011. The new oral anticoagulant drug functions to selectively inhibit a specific single factor from among the known coagulation factors, and moreover, it is characterized in having a short half-life. During tooth extraction, surgery while continuing antithrombotic drugs is suggested regarding warfarin in order to avoid complications of thrombus/embolism events with guidelines established; however, no consensus regarding whether or not to continuously carry out dental surgery measures has been acquired regarding new anticoagulant drugs. We hereby report on our experience regarding minor surgeries carried out on patients taking new oral anticoagulant drugs.

<Methods>

Surgery was carried out on 7 patients and 8 cases while continuing new oral anticoagulant drugs, including dabigatran and rivaroxaban. The types of surgery were as follows: 13 tooth extractions (including extraction of 2 impacted teeth), 1 radicular cyst excision, and 1 second implant surgery.

<Results>

Minor dental surgeries were carried out while taking new anticoagulant drugs, but no serious hemorrhagic complications were observed.

<Conclusion>

In order to avoid complications such as serious cerebral infarction, etc., it is believed that minor dental surgeries should be carried out while taking new anticoagulant drugs.