Massive Odontoameloblastoma Arising in the Maxilla

Masanori Kudoh III DDS, PhD, Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Hiroyuki Harada DDS,PhD, Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Yuriko Sato DDS,PhD, Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Ken Omura DDS,PhD, Oral and Maxillofacial surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Yoshimasa Ishii DDS,PhD, Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Surgery, Ebina General Hospital, Ebina, Japan
Odontoameloblastoma is an extremely rare mixed odontogenic tumor with both epithelial and mesenchymal components.The term Odontoameloblastoma first appeared in the 1971’s WHO classification (Pindborg et al.) and is definied as follows”: a neoplasm that includes odontogenic ectomesenchyme in addition to odontogenic epithelium that resembles an ameloblastoma in both structures and behavior. Because of the aggressive nature and risk of recurrence of the tumor, complete extirpation is essential.

Here, We reported an extremely rare case of massive odontoameloblastoma arising in the maxilla and occupying maxillary sinus.

  In April 2013, a 11-year-old boy patient referred to our department for a painless and large mass of the right maxillary region. Panoramic X-ray showed an unilocular cystic lesion in the right maxilla containing calcified mass in the lesion associated with impacted tooth. Computed tomography showed the cystic lesion including calcified structures, measuring 3.6×3.1×2.7cm. In July 2013, he underwent tumor extirpation combined with impacted tooth extraction. Histopathological diagnosis showed odontoameloblastoma.

No recurrence was noted 7 months after the operation.

Keywords: Odontoameloblastoma, mixed odontogenic tumor, maxillary sinus.